Identification of rat T and B lymphocytes by surface marker analysis
نویسندگان
چکیده
منابع مشابه
Surface Globulins of T and B Lymphocytes
The concept that lymphocytes recognize antigens by means of a surface receptor molecule of immunoglobulin (Ig) character has come to be widely accepted (1-3). Direct study of such receptors in the mouse by means of antiglobulin reagents labeled with either fuorescent (4, 5) or radioisotope (3, 6-8) markers has revealed a dense coating of surface immunoglobulins on nonthymus-derived or B lymphoc...
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A method is described whereby antisera raised in rabbits to rat thoracic duct lymphocytes were made specific for the plasma membrane antigens of T and B lymphocytes. These lymphocyte-specific antisera were used in immunofluorescence assays to study the distribution of B and T cells in lymphocyte containing tissues and body fluids of the rat. Rabbit antirat B-cell serum (ALS(B)) reacted selectiv...
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Human peripheral lymphocytes were investigated for receptors binding Epstein-Barr virus (EBV) because of the regular association of this virus with infectious mononucleosis and Burkitt's lymphoma. This was done by a cytoadherence technique where virus-producing cells, displaying fresh viral determinants in their cytoplasmatic membrane, were mixed with lymphocytes. Unfractionated lymphocytes wer...
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By using the two criteria (a) high density of immunoglobulin determinants on the cell surface and (b) presence of receptors for C'3 on the cell surface for defining bone marrow-derived lymphocytes, it is indirectly shown that all or at least a major population of human thymus-derived lymphocytes under certain conditions will form nonimmune rosettes with sheep red blood cells (SRBC). Almost all ...
متن کاملRegulation of human gut B lymphocytes by T lymphocytes.
The aims of this study were first, to assess whether or not immunoglobulin secretion from human gut mucosal B lymphocytes can be modified by T lymphocytes, and second whether human gut mucosal T lymphocytes are capable of regulating mucosal B lymphocyte function. T and B lymphocyte enriched cell populations were isolated from gut mucosa and co-cultured in varying proportions. Addition of T lymp...
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ژورنال
عنوان ژورنال: Laboratory Animals
سال: 1982
ISSN: 0023-6772,1758-1117
DOI: 10.1258/002367782780908715